Cytokinins are plant hormones which have long been associated with cell division and plastid differentiation. Recently, they have been found to play a central role also in the growth of plant tumors. Certain phytopathogenic bacteria, notably Agrobacterium tumefaciens and Pseudomonas syringae pv. savastanoi, can incite tumors on dicotyledonous plants and such tumors exhibit growth which is characteristic of the presence of excess auxin and cytokinin. Genes specifying cytokinin biosynthesis have now been isolated from both sets of bacteria. The genes encode (...) prenyl transferase responsible for cytokinin biosynthesis which, upon expression in E. coli,cause the production of the active cytokinin, zeatin. Expression of these genes in association with the plant is responsible for at least part of the tumor phenotype, although the molecular mechanisms of infection by these bacteria are apparently quite dissimilar. There is extensive homology between the cytokinin biosynthetic genes from the two sets of bacteria. (shrink)

New Blackfriars, Volume 103, Issue 1105, Page 396-407, May 2022.

In this paper I present a dynamic-epistemic hybrid logic for reasoning about information and intention changes in situations of strategic interaction. I provide a complete axiomatization for this logic, and then use it to study intentions-based transformations of decision problems.

This is the introduction of the special issue,.

Objectives To review the extant literature on HIV criminal laws, and to determine the impact of these laws on public health practice.Methods The available research on this topic was obtained and reviewed.Results The extant literature addressed three main topics: people's awareness of HIV criminal laws; people's perceptions of HIV criminal laws; and the potential effects of HIV criminal laws on people's sexual, HIV-status disclosure and healthcare-seeking practices. Within these categories, the literature demonstrated a high level of awareness of HIV criminal (...) laws, but a poor comprehension of these laws. For perceptions, on the whole, the quantitative research identified support for, while the qualitative literature indicated opposition to, these laws. Lastly, the behavioural effects of HIV criminal laws appear to be complex and non-linear.Conclusions A review of the extant literature from a public health perspective leads to the conclusion that HIV criminal laws undermine public health. (shrink)

Recently, focus groups and qualitative interviews with nurses who provide frontline care for persons living with HIV highlighted the contentiousness surrounding the seemingly innocuous activity of counselling clients about HIV‐status disclosure, hereafter disclosure counselling. These empirical studies highlighted that while some nurses felt they should instruct clients to disclose their HIV‐positive status if HIV transmission were possible, other nurses were equally adamant that such counselling was outside the nursing scope of practice. A review of these opposing perceptions about disclosure counselling, (...) including an examination of the empirical evidence which supports each point, revealed that the dichotomous arguments needed to be nuanced. The empirical evidence about serostatus disclosure neither supported nor refuted either of these assertions; rather, it substantiated parts of each. To create this understanding, both empirical and theoretical works are used. First, the results of empirical studies about serostatus disclosure, or lack thereof and HIV transmission is presented; as part of this, Marks and Crepaz's HIV disclosure and exposure framework is examined. Second, the work of Michel Foucault on disciplinary and pastoral power is drawn from. The outcome is a nuanced understanding about the interrelationships between disclosure counselling and nursing practice and a final interpretation about what this understanding means for public health practice. (shrink)

A deontological approach to surgical ethics advocates that patients have the right to receive the best care that can be provided. The ‘learning curve’ in surgical skill is an observable and measurable phenomenon. Surgical training may therefore carry risk to patients. This can occur directly, through inadvertent harm, or indirectly through theatre inefficiency and associated costs. Trainee surgeon operating, however, is necessary from a utilitarian perspective, with potential risk balanced by the greater societal need to train future independent surgeons.New technology (...) means that the surgical learning curve could take place, at least in part, outside of the operating theatre. Simulation-based deliberate practice could be used to obtain a predetermined level of proficiency in a safe environment, followed by simulation-based assessment of operative competence. Such an approach would require an overhaul of the current training paradigm and significant investment in simulator technology. This may increasingly be viewed as necessary in light of well-discussed pressures on surgical trainees and trainers.This article discusses the obligations to trainees, trainers and training bodies raised by simulation technology, and outlines the current arguments both against and in favour of a simulation-based training-to-proficiency model in surgery. The significant changes to the current training paradigm that would be required to implement such a model are also discussed. (shrink)

The lateralized ERP N2pc component has been shown to be an effective marker of attentional object selection when elicited in a visual search task, specifically reflecting the selection of a target item among distractors. Moreover, when targets are known in advance, the visual search process is guided by representations of target features held in working memory at the time of search, thus guiding attention to objects with target-matching features. Previous studies have shown that manipulating working memory availability via concurrent tasks (...) or within task manipulations influences visual search performance and the N2pc. Other studies have indicated that visual vs. spatial working memory manipulations have differential contributions to visual search. To investigate this the current study assesses participants' visual and spatial working memory ability independent of the visual search task to determine whether such individual differences in working memory affect task performance and the N2pc. Participants completed a visual search task to elicit the N2pc and separate visual working memory and spatial working memory assessments. Greater SPWM, but not VWM, ability is correlated with and predicts higher visual search accuracy and greater N2pc amplitudes. Neither VWM nor SPWM was related to N2pc latency. These results provide additional support to prior behavioral and neural visual search findings that spatial WM availability, whether as an ability of the participant's processing system or based on task demands, plays an important role in efficient visual search. (shrink)

Introducing analytic philosophy -- F.H. Bradley and monistic idealism -- G.E. Moore on idealism, the good, and common sense -- Gottlob Frege : logic and the philosophy of language -- Bertrand Russell on relations, descriptions, and knowledge -- E.E. Constance Jones on language and logic -- Ludwig Wittgenstein on language and philosophy -- Logical empiricism : meaning, metaphysics, and mathematics -- Susan Stebbing on logic, language, and analysis -- W.V.O Quine on analyticity and ontology -- Analytic philosophy since 1950.

in Sounds and Perception: New Philosophical Essays, ed. by Matthew Nudds and Casey O’Callaghan (Oxford University Press, forthcoming in 2008).

Rudolf Carnap and W. V. O Quine have long been seen as key figures of analytic philosophy who are opposed to each other, due in no small part to their famed debate over the analytic/synthetic distinction. This volume of new essays assembles for the first time a number of scholars of the history of analytic philosophy who see Carnap and Quine as figures largely sympathetic to each other in their philosophical views. The essays acknowledge the differences which exist, but through (...) their emphasis on Carnap and Quine's shared assumption about how philosophy should be done-that philosophy should be complementary to and continuous with the natural and mathematical sciences-our understanding of how they diverge is also deepened. This volume reshapes our understanding not only of Carnap and Quine, but of the history of analytic philosophy generally. (shrink)

This research applies the impression management theory of exemplification in an accounting study by identifying and measuring differences in both auditor and public perceptions of exemplary behaviors. The auditors were divided into two groups, one of which reported self-perceptions (A-S) while the other group reported their perceptions of a typical auditor (A-O). There were two separate public groups, which gave their perceptions of a typical auditor and were divided based on their levels of accounting sophistication. The more sophisticated public group (...) was comprised of bank loan officers (LO) while the less sophisticated public group consisted of investment club members (IC). Comparisons were made on 30 behaviors contained in the AICPA Code of Professional Conduct, which served as the basis for the research instrument. Profile analysis, a special form of MANOVA technique, was used to analyze the results. A-S perceptions were the highest of the four treatment levels and were significantly higher (i.e., more exemplary) than the perceptions of both the A-O and LO groups. The more sophisticated user group (LO) provided the lowest perceptions of the four treatment levels. For at least four of the six measures, the LO treatment group perceived the typical auditor to be less exemplary than both the IC and A-O treatments. There were no differences in perceptions between the A-O group and IC. Additional analysis revealed that auditors overrated the degree to which the public relied on financial statements. However, both public groups reported a reasonably high level of reliance on financial statements when making decisions. (shrink)

Nanoparticles of cobalt ferrite prepared by the co-precipitation method with crystallite size varying from 4.7 to 41 nm have been characterized by positron annihilation lifetime spectroscopy. Three lifetime components are fitted to the lifetime data. The shortest lifetime component is attributed to the delocalized positron lifetime shortened by defect trapping. The intermediate lifetime is assigned to the positron annihilation in diffuse vacancy clusters or microvoids at the grain boundaries and at the grain-boundary triple points. The longest component corresponds to the (...) pick-off annihilation of ortho-positronium formed at the larger voids. The variations in these lifetimes and their relative intensities with annealing temperature and crystallite size have been studied in detail. (shrink)

The view that plural reference is reference to a set is examined in light of George Boolos's treatment of second-order quantification as plural quantification in English. I argue that monadic second-order logic does not, in Boolos's treatment, reflect the behavior of plural quantifiers under negation and claim that any sentence that properly translates a second-order formula, in accordance with his treatment, has a first-order formulation. Support for this turns on the use of certain partitive constructions to assign values to variables (...) in a way that makes Boolos's reading of second-order variables available for a first-order language and, with it, the possibility of interpreting quantification in an unrestricted domain.A first-order theory, T(D), is developed on the basis of Boolos's treatment of simple plural definite descriptions extended to Richard Sharvy's general theory of definite plural and mass descriptions. I introduce a primitive predicate, o, for the relation of the referent of a singular description to that of its plural. If o is simply added to T(D), is definable in T(D), and the result is inconsistent. If o is added to a theory with axioms for the fragment of T(D) I call D-mereology, the result is a natural basis for the development of a pluralized Zermelo set theory. This theory, however, is inconsistent in an unrestricted domain, unless it is recast as a second-order theory of sets interpreted in Boolos's way. (shrink)

This is a reply to Casey O'Callaghan and Jonathan Westphal’s comments on Seeing Dark Things: The Philosophy of Shadows. Both attempt to soften the blow to intuition that comes from the most controversial thesis of the book: we see the backs of back-lit objects. Each characterizes the viewing of silhouettes as a kind of marginal seeing that only discloses shapes, sizes and location. In response, photographs are presented to show that silhouettes are typically three-dimensional and they often have internal structure. (...) Consider the silhouette of a bird fluttering inside a cage; we see more than the outline of the cage. Orbiting this main point are subsidiary points about the distinction between shade and shadows, the nature of occlusion, the color black, and peculiarities of absent absences. (shrink)